Evaluation of risk factors associated with SARS-CoV-2 transmission.

OBJECTIVE: Coronavirus disease 2019 (COVID-19) has caused high morbidity and mortality worldwide. Since there is not enough evidence of risk factors of SARS-CoV-2 transmission, this study aimed to evaluate them. METHODS: This survey-based study was conducted across 66 countries from May to November 2020 among suspected and confirmed individuals with COVID-19. The stepwise AIC method was utilized to determine the optimal multivariable logistic regression to explore predictive factors of SARS-CoV-2 transmission. RESULTS: Among 2372 respondents who participated in the study, there were 1172 valid responses. The profession of non-healthcare-worker (OR: 1.77, 95%CI: 1.04-3.00, p = .032), history of SARS-CoV or MERS-CoV infection (OR: 4.78, 95%CI: 2.34-9.63, p < .001), higher frequency of contact with colleagues (OR: 1.17, 95%CI: 1.01-1.37, p = .041), and habit of hugging when greeting (OR: 1.25, 95%CI: 1.00-1.56, p = .049) were associated with an increased risk of contracting COVID-19. Current smokers had a lower likelihood of having COVID-19 compared to former smokers (OR: 5.41, 95%CI: 1.93-17.49, p = .002) or non-smokers (OR: 3.69, 95%CI: 1.48-11.11, p = .01). CONCLUSIONS: Our study suggests several risk factors for SARS-CoV-2 transmission including the profession of non-healthcare workers, history of other coronavirus infections, frequent close contact with colleagues, the habit of hugging when greeting, and smoking status.

Since there is not enough evidence of risk factors of SARS-CoV-2 transmission, this study aimed to evaluate them. The risk of SARS-CoV-2 infection was higher among non-healthcare workers and among those who had a history of being tested positive for SARS-CoV or MERS-CoV before the COVID-19 outbreak. The habit of frequent contact with colleagues or hugging when greeting significantly increased the risk of being infected with SARS-CoV-2. The current smokers had a lower risk of getting infected with SARS-CoV-2 than others who had a habit of smoking tobacco in the past or who had never smoked.

The simultaneous crises of dengue and COVID-19 in Pakistan: a double hazard for the country's debilitated healthcare system.

Dengue fever is an arthropod-borne viral illness caused by four dengue virus serotypes (DENV 1-4), spread by Aedes mosquitos. Common symptoms of dengue include high peak temperature, headache, myalgia, and malaise following infection, with a rash emerging after 3 to 4 days. More than half of the world's population lives in dengue-endemic areas. Every year, around 100 million dengue cases are reported, with Southeast Asia comprising the majority. Nearly every day, there is a breakout of dengue infections in many areas of Pakistan, in addition to the ongoing COVID-19 pandemic. As a result, combating the dual burden of dengue and COVID-19 is difficult for the nation's healthcare system. Misdiagnosis owing to overlapping symptoms with COVID-19, overburdening of the healthcare system, and a lack of appropriate vaccination are some of the obstacles for dengue infection management. The government of Pakistan is pursuing a variety of measures to combat dengue fever outbreaks, including, The Pakistan Red Crescent Society was asked by the Department of Malaria Control Program to aid in promoting awareness and organizing clean-up campaigns in polluted regions and stagnant water for vector control.

Emergence of highly infectious SARS-CoV-2 variants in Bangladesh: the need for systematic genetic surveillance as a public health strategy.

Bangladesh, a low-middle-income country in South Asia is facing one of its worst public health emergencies due to the COVID-19 pandemic. The increase in the number of cases from the disease, since the second half of March 2021, can potentially cause the health system overload, and has, as one of the main reasons, the non-compliance with measures of social distance and the emergence of the variants of concern in the country. This increase in the contagion curve can also provide a favorable environment for the occurrence of more mutations in the structure and genome of the virus. Therefore, there is an urge to carry out genomic surveillance programs in order to identify, monitor and characterize these variants, and understand whether the vaccines currently used are effective against them.

False-Negative RT-PCR Findings and Double Mutant Variant as Factors of an Overwhelming Second Wave of COVID-19 in India: an Emerging Global Health Disaster.

RT-PCR is considered to be the standard gold diagnostic test for detecting COVID-19 causing SARS-CoV-2. Recent reports and recent pieces of evidence from scientific literature, however, tell a different story. There have been speculations of SARS-CoV-2 escaping the RT-PCR because of the series of mutations it has gone through. It is possible that host-dependent RNA editing and high person-to-person transmission have equipped the virus with mutations enabling it to spread faster and even evade the RT-PCR. Added to this is burnout among healthcare workers and technicians handling the RT-PCR machines and sampling. All of these factors may be working in unison to result in the deluge of false-negative cases India is facing during the second COVID-19 wave. The mutant strains are spreading to other parts, posing challenges to the whole world. These circumstances warrant supplementary diagnostic tests such as serological and radiological findings to deal with cases of high clinical suspicion. Even one misdiagnosed COVID-19 patient poses a risk to hundreds of others in the vicinity. Healthcare workers' burnout also has to be dealt with. Erroneous staff should be re-trained.

Kumbh Mela Religious Gathering as a Massive Superspreading Event: Potential Culprit for the Exponential Surge of COVID-19 Cases in India.

The Kumbh Mela is a significant religious gathering of millions of Hindu devotees in India. It is celebrated on certain auspicious days in the Hindu calendar and attracts millions of pilgrims across the country. Despite the religious intention of millions of Hindu devotees, it raised public health concerns as it became a massive superspreading event for COVID-19. Being the second most populous country, India became the second most affected country during the COVID-19 pandemic. In addition to the arrival of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and the presence of the double mutated variant, which was first identified in India, the Kumbh Mela probably aggravated the country's COVID-19 situation which resulted in an uncontrollable second wave. Several cases of COVID-19 across India had been contact-traced to returnees from the event who acted as a nidus to help spread the infection. As a consequence, India's healthcare system was severely challenged as a result of the overwhelming hospitalizations and increasing fatalities resulting in an acute manpower shortage in healthcare along with the depletion of drugs and medical supplies despite being one of the largest pharmaceutical hubs globally. Leaders and governments around the world should learn from India's experience and thereby take preventive measures to manage potential superspreading events to curb the spike of COVID-19 cases.

How to avoid fake COVID-19 vaccine passports as a travel requirement?

The Philippines has recently eased its local travel restrictions among fully vaccinated individuals. Filipinos who wish to travel locally will only need to present their vaccination cards as their passports for interzonal and intrazonal movement within the country. However, a few days after the release of the new resolution pertaining to the coronavirus disease 2019 (COVID-19) vaccination card as a travel requirement, the Department of Health suggested to review the latest policy since many local government units expressed their disapproval in the new protocol. One of the issues raised is the authenticity of COVID-19 vaccination cards. These cards vary per local government and most of them do not have machine-readable codes nor security features. Thus, they can be easily falsified and counterfeited. In addition, the local governments do not have access to the national database of the COVID-19 vaccination status of every individual, which can be extremely challenging for them. In this correspondence, recommendations were provided to avoid fake COVID-19 vaccination cards as passports for travel purposes.

COVID-19 and mucormycosis syndemic: double health threat to a collapsing healthcare system in India.

In addition to the overwhelming and uncontrollable second wave of COVID-19 in India, the country is also dealing with an outbreak of mucormycosis, a deadly fungal infection, which is affecting thousands of COVID-19 patients. With the increasing number of cases of mucormycosis and a fatality rate of 50%, many Indian states and union territories have declared an epidemic of black fungus due to its unprecedented emergence, which has adversely affected the already debilitated health system of the country. The advent of the new fungal epidemic in the country is due to the overdosage, panic and injudicious use of corticosteroids among COVID-19 patients, as well as their pre-existing medical history of diabetes, given that India is the diabetes capital of the world. Thus, there is an urgent need to address this public health concern by having nationwide surveillance, diagnostic and management system of the disease, along with public awareness and education to combat the syndemic of COVID-19 and mucormycosis in the country.

Employing medical anthropology approach as an additional public health strategy in promoting COVID-19 vaccine acceptance in Bhutan.

Bhutan has been commended for their COVID-19 vaccination campaign, in which the country became the fastest in the world to inoculate nearly all of its adult population in just a few weeks. As a profoundly religious Buddhist kingdom in South Asia, the country successfully utilized a very unique strategy in promoting COVID-19 vaccine acceptance nationwide. Bhutan incorporated religion, culture, and tradition in their campaign wherein the royal government collaborated with the Zhung Dratsang, the country's central monastic body, in deciding the most auspicious day for the launch of their vaccination rollout by avoiding the one-month long Dana, selecting the first person to be vaccinated in accordance to the Buddhist astrology, and leading the country in chanting the Sangay Menlha, a mantra believed by many as a powerful prayer in warding off diseases. The launch turned out as a feast for all Bhutanese since it seemingly marked the beginning of the last phase of their COVID-19 struggle. Incorporating medical anthropology in public health approaches can greatly influence the public, especially when the people are deeply rooted in folk beliefs. This unique strategy can be emulated by many localities with strong influence of cultural traditions and folk beliefs.

Typhoons During the COVID-19 Pandemic in the Philippines: Impact of a Double Crises on Mental Health.

The Philippines, a disaster-prone country in Asia, was hit by 22 tropical cyclones during the coronavirus disease (COVID-19) pandemic. Among the 22 tropical cyclones, 1 is recorded as the strongest tropical cyclone that made a landfall in world history. The recurrent typhoons in the Philippines during the pandemic have led to a long-lasting humanitarian crisis as hundreds of thousands of houses and collateral assets have been destroyed due to floods and landslides, leaving thousands of Filipinos homeless. Concurrently, the country has been experiencing a rise in the number of COVID-19 cases due to overcrowding in evacuation centers and lack of social distancing. The simultaneous existence of natural disasters and pandemic has caused devastating and detrimental effects to the mental health of Filipinos. Nonetheless, the Government of the Philippines, together with the World Health Organization and other humanitarian organizations, has been working hand-in-hand in implementing mental health approaches and providing psychological interventions to Filipinos who were greatly affected by the natural disasters and the COVID-19 pandemic.

Demographic, gadget and internet profiles as determinants of disease and consequence related COVID-19 anxiety among Filipino college students.

In the context of the nationwide shift to online learning due to the COVID-19 pandemic and its possible effect on mental health, this study investigated the relationship between demographic, gadget and Internet profiles, and disease and consequence related COVID-19 anxiety among Filipino college students. This is a quantitative cross-sectional study. A total of 952 students participated in the online survey. Descriptive and inferential statistics were used to draw insights from the data. Findings suggest that majority of the student respondents had high levels of disease and consequence related COVID-19 anxiety. Students from poorer households, who do not own laptops and desktop computers, and those with limited Internet connection exhibited higher levels of disease-related COVID-19 anxiety. Younger, poorer, female students who were enrolled in lower year levels, do not own laptops or tablets, and have limited or borrowed Internet connectivity demonstrated higher levels of consequence-related COVID-19 anxiety.